I upgraded my Mavic Aksiums a few years back with a set of custom wheels. It's a pretty basic build: Velocity Aerohead rims with White Industries hubs. Sapim double butted spokes; 24 (I think) in the rear and 20 in the front. I love them, and my husband has a similar set. We both love them. I shied away from prebuilt wheels because many are overbuilt for someone my size. I also didn't want bladed spokes. I think you can often get more bang for your buck with handbuilts.
Ron Ruff at White Mountain Wheels built my husbands wheels. If I were in the market again, I'd call him or another reputable builder. Tell him what kind of riding I do on what kind of roads and let him recommend a build within my budget and weight.
Live with intention. Walk to the edge. Listen hard. Practice wellness. Play with abandon. Laugh. Choose with no regret. Continue to learn. Appreciate your friends. Do what you love. Live as if this is all there is.
--Mary Anne Radmacher