I used to be bigger. When you bike and work out at the gym, you lose the weight. Anyway, I went through saddle discomfort when I was bigger and found the Selle An-Atomica, which is leather with a slot, a version for people over 180 lbs, and the saddle has an adjustment to firm up the leather if necessary. I put a lot of miles on the saddle, lost the weight, wore out the saddle, and bought a new saddle. I've put over 6,000 miles on the bike this year, so you can see I ride a lot. Oh yeah, I ride a Trek Pilot 5.2, and this saddle really works well on the Pilot.

http://www.selleanatomica.com/dollar%20buyer.htm#Titanico_LD_Saddle_Second_Skin_Watershed_Leather_-_$179.98_

You have to scroll around to make sure you view the saddle. There are color choices and the version for heavier cyclists.

The saddle is sort of like a leather Brooks, except for the slot. I can't even say there is a break-in period. Your butt lands on the saddle, and it is a great sigh of "oh yeah isn't this wonderful" and that is how the saddle is.