I just got a second wheelset for my Fuji Cross Comp. Stock it has 36/46 up front and a 10 speed 12-25 in the rear. Im on the Front Range, so I know those "hills" you're referring to
My second set will have slicks on it (stock has xc knobbies), and I ordered an 11-28 for the cassette on it. Im excited to have that 28 on the low end AND that 11 for some extra speed. Cant wait for it to come in!