Can't speak for myself, but it has done and continues to do wonders on our dog. Shortly after we got her, at age 2, she was diagnosed with hip dysplasia. It was so bad she could hardly stand up. The vet suggested glucosomine with msm and within a few months, she was chasing frisbees again. She's 8 now, still gets her daily dose and is doing well. She had to have an xray about 6 months ago and the vet could not believe how well she walks/hikes/runs, or that she does it at all considering how bad her hip looked in the xray. It apparently helps her pain quite a lot.