I work in a mostly male unit and I agree with Maxxxie, you've got to give it right back to him, tactfully! He is obviously intimidated by you and his failed attempts at relationships with females are represented by you and your independence. That just pisses him off to see another independent woman that he can't control. He has found a topic that he's knows is getting to you so he keeps jabbing. When the time is right, jab back. There is a fine line between joking around and harassment, let him know he is crossing it. If that doesn't work, get your boss involved. It is after all her responsibility to supervise. Some people just need to be on a leash! Good luck!