my doctor told me that they considered 2 years of HRT to be the max, i did that several years ago now. So i delayed my bones from thinning for two years, now they are thinner. My hair has never been great, but i haven't noticed any big difference. where I HAVE changed drastically, and I am telling you guys this despite the fact that i am shy and embarrassed. but the girly bit parts have lost the natural padding that used to be there and the actual quality of the flesh there has changed as well. i tear and bruise there so easily that it is ridiculous. It sucks.