My mom swears by Sam-e (she said it took a couple months of consistent use to notice anything, and then the difference was remarkable). She said that her rheumotologist advised against glucosamine/chondroitin (sp?) as ineffective. She's also been advised to keep her omega-3mega-6 ratio as close to 1:2 or even better 1:1 as much as possible (the typical american diet is closer to 1:20 or more!). She wants to stay away from rx meds as long as possible. Warm water pool therapy seems to be helping her as well.

I believe my mother gets her supplements through VitaCost and said that the prices are even much better than Costco. Before retiring, with a written note from her dr. including her diagnosis of rheumatoid arthritis, she was able to get FSA reimbursement for her supplements.