I DO get knee pain if my saddle's too far forward. It's a very specific, localized pain though. I've gotten to the point that if I feel that specific pain, I know I need to push my saddle back a little. It feels like a tendon or ligament, and it's directly above my kneecap. Moving my saddle back during a ride can make it disappear suddenly, even if it's been bothering me for miles.

But the pain I get from saddle position is quite different than what you're describing... it really feels like there's one tendon I'm straining, it's not generalized like your pain. So I have no idea if your pain is related to the saddle changes, but it *is* possible.

Anything else different you've been doing? (Lifting weights, playing tennis, etc.)...