My Bianchi has the original saddle (five years old) and just this season it's really getting to me. Do saddles have a life span?

Mostly what bothers me is that my delicate area has too much pressure and feels fairly irritated (though never abraded) soon into a ride. I wear a good chamois and use lube. Lately I feel I am wiggling around all the time and never really comfortable.

So I need a new saddle. Are women's saddles the way to go? Does the cut out area really help? Any recommendations?