I wear either the Sugoi (not a clue sry) or the Performance Ultra Gel Shorts for all my rides rather they're 12 miles or 112 miles. I don't use any chamois butter or creme and I don't have any problems but..........I have a Great saddle and I've made sure it's set just right for me.
If the Flex shorts still don't work for you, you might want to consider a saddle change. To each her own but if you're riding the saddle that came with your bike - it's probably a Bontrager. I and several other women here think the Bontrager was made for the sole purpose of torturing it's rider!
Life should NOT be a journey to the grave with the intention of arriving safely in an attractive and well preserved body, but rather to skid in sideways, champagne in one hand, strawberries in the other, body thoroughly used up, totally worn out and screaming: "Yeah Baby! What a Ride!"