I am definitely not top heavy (think 34A, barely) and own the Velo Bella jersey (older version without the Kona logo, much nicer to me, and I constantly get complimented on it). It's definitely a "race cut", so I'm not sure even the larger version will fit large boobage. I would place more hope in the iris one (which is BEAUTIFUL!). But I could be wrong. You should email Susan from TE about it, these girls know everything.