while I don't have osteoarthritis and so am not sure whether this applies or not, my right knee is missing the anterior crucate ligament and about 80% of the cartiledge was removed because it was torn and pressing on nerves- thanks to a careless driver who never saw me in the pedestrian crosswalk until my hand came through his windshield. This was about 40 years ago so I have had that many years of learning to keep my knee aligned and strengthening the muscles that support the knee- however I will say that I didn't have any problems and much prefer the clipless pedals because being clipped in helps me keep my knee in alignment. I do have my clip on the bad knee set somewhat loser and always unclip with that foot first. Just take time to experiment and make sure you get the tension right and align your knees.
marni
marni
Katy, Texas
Trek Madone 6.5- "Red"
Trek Pilot 5.2- " Bebe"
"easily outrun by a chihuahua."