A friend of mine who is about my size (she's about 5'3", I am closer to 5'4") has the 42. I borrowed it and liked it. I think they run a bit bigger than my Redline Conquest, which is a 44...they're probably pretty comparable. I think I'd be going through the same dilemma that you are. Do you plan to do CX races with it? I might encourage you to go smaller if you're between sizes (and maybe try a longer stem). If you are planning to ride it more on the road you might like the 46 more.