I've had my bike since last Aug and since then I've put about 15 saddles on her. Some I knew right away weren't for me (too narrow usually) and took them back. The gel ones were the worst actually. Funny thing is, my mtb saddle (Specialized) was the best one out of all of them I tried on so I kept putting that one back on in between trials. It wasn't perfect, but I wasn't tortured either, even after a metric. I tried out both of Kit's saddles. She has a Brooks B-17 and a Selle Anatomica and I hated them both from the start. I can honestly say, I think I finally found the one that is right for me. I just got a Selle San Marco from Performance in the 155 width and I love it. No discomfort in the least. I recently bought some tri shorts too (with the very thin padding) and still feel just ducky, no bruising or rub.
As these ladies said... everyone is different. Not just the width of our sit bones but how our posture is, whether we have thigh rub, if the seat is maybe a little too far front or back, etc. (I put a 0 offset seat post on and that was the final adjustment I needed. Short femurs.) Find one that fits your sit bones and that doesn't hurt you in those spots. Then pay attention to where your seat is in relation to your pedals, tipped up/down/flat and how you hold your torso.
BTW, both REI and Performance have a 100% satisfaction guarantee so you can try out as many as you want.
Good luck.