I'm 5'2" with very small hands. I have an Orbea Onix Dama with the Ultegra components and find it very comfortable on my hands. I also did some demos on other bikes with the 105s and Tiagra set-ups that were not WSD bikes and actually felt unsafe because I was so uncomfortable braking and shifting. I also was on the Ruby with the 105s and did not find problems with the handlebars - but I just fell in love with my Orbea - the bike just disappeared beneath me I was so comfortable, so that's what I went with. I found it to be more the handlebars than the components when it comes to hand comfort and LOVE my Ultegra components. The best advice I can give is try as many as you can before you make a decision....the Orbea was not even a bike I was considering in the beginning.