I have arthritis in both knees and I can testify to the fact that even with all the cycling I do, I still, from time to time have problems.

I manage it by taking MSM and Glucosamine Sulfate. I get both of these from Innate Source as they have the pure stuff. I get it in powder form and mix it with honey, vinegar (that's to help plaque buildup), and hot water. You can take it with other stuff, this is just what I do.

I take calcium that I get from EZORB- that also seems to help.