Prednisone

[Aggie_Ama]

DH was on a pretty high dose (60 mg/daily) for 6 weeks last year for his Crohn's. It made my normally mild mannered husband irritable and short tempered. He also had crazy mood swings including feeling depressed/hopeless. Some of his mood I attribute to his life changing diagnosis of Crohn's, it is pretty hard to hear you have a chronic disease. He also gained 30 lbs but again he was on them for 6 weeks. Just follow the doctors dosage and make sure he tapers you back off. I am pretty sure you cannot quit cold turkey.

[Possegal]

no, you can't quit cold turkey. the reason being, the cortisone that is normally secreted by your adrenal gland will stop being secreted because your body senses that you have enough, this feedback inhibition is one of the body's more amazing methods, i think. as you taper off an exogenous corticosteroid, your body detects less so gears up to secrete more. if you stopped all at once, your adrendal gland would take a little time to get the signal to start secreting it again so you would have a short period of time where you wouldn't have enough of it in your system. that's pharmacology 101, just for the information.

and the word you may be looking for is spinal stenosis?

for me, even doing a 1-2 week round of predisone, i can eat like a horse! i have to make a real concerted effort to eat like normal. i've never had mood or sleep disorders from 1-2 week doses (and with my asthma i've actually done those rounds way more times than i care to recall). though it is certainly possible.

[bmccasland]

So I was only on it for 5 days after my allergic reaction to food. Made me jittery, as if seriously buzzed on coffee. Maybe the coffee I was drinking didn't help...
But I did walk down to the pharmacy and ask the pharmacist. Wasn't sure if I was going nuts or what. Apparently one of the side effects can make one jittery, and I had it. Got better when I stopped.

[makbike]

As others have said follow the directions. You can't and shouldn't stop this drug cold turkey. Pred can make you drink more, urinate more and eat more. As others have also pointed out it can cause you to be moody. It can, over time, also upset your stomach. You might try taking an acid reducer one hour before you take the pred. Check with your doctor as to the dose you need.

The good news is you should start to feel better pretty soon. Other aches and pains should also disappear.

Hang in there and keep us posted.

[Sheesh]

I'm only familiar with what Prednisone does to my dog, Murphy (pictured in Avatar). He has seasonal allergies which causes him to lick and pick at his feet until they're red and scabbed over. The vet prescribed predisnone and he didn't respond well - could not control his bladder. Even half the prescribed dosage caused him to pee in our bed. Needless to say, we don't give it to him anymore.

Hopefully it doesn't have the same reaction in humans!