Prednisone typically has side effects not the least of which is mood changes.

The nastier side effects you hear about (weakened collagen tissue, loss of bone mass...) come with long term use. Using the meds for only 2 weeks should not cause any big issues, but you definitely do not want to be on them long term.

This is a very effective drug for suppressing the infammatory response. It should start to make you feel better very quickly.

And do follow the MDs advise precisely when it comes to tapering off them.