I rode with a blister on my crotch (okay between my thigh and my crotch) for one full year. I say, suck it up! You are an athlete, pain is your friend.

Just kidding - but I did ride with a blister for a year. It just kept deflating and refilling. I showed it to my dermotogists and she said, "yuck" and told me to come in when I was ready to take a break from the bike and she would "take it out and sew it up." I never had to - I got a new seat and, eventually, it dissappeared. I miss it.