I did this route last year (self-supported) as part of the Great Allegheny Passage. We began in Boston, PA. My girlfirend & I did it over a 5 day period averaging about 60-65 miles per day. For the C&O canal portion, we stayed in Cumberland (Holiday Inn), Hancock (Super 8?), and Harper's Ferry (Historic Hilltop House Hotel). It was a great ride. Enjoy!