This gives me the giggles, as I had 105 and HATED it...I never could get the hang of it. But SRAM was intuitive from the get-go.
Speaking of Synapse vs. CAAD, my first bike was an aluminum Synapse, new bike is a carbon SuperSix, which has identical geometry to the CAAD, just in carbon. The SuperSix is a better bike for me, but only because the Synapse was a bit too relaxed, too short through the top-tube (I'm all torso), and less responsive...when I started riding I didn't know that I would end up liking to ride fast-ish. I also didn't know how godawful aluminum would be on our chip-sealed roads.
I agree with others that you owe it to yourself to try a Ruby. There's a reason that bike is so popular. My hubby has a men's Roubaix and adores that bike...it's comfortable, but also very happy to go hard and fast. I've seen so many people on TE talk about the Roubaix/Ruby as a really perfect compromise between pure comfort and pure performance. I would have tried one, myself, except our favorite shop doesn't carry Specialized (and we're not real fond of the ones around here that do) and when I saw that orange and white SuperSix with the exact components I wanted there was no averting my eyes long enough to look at anything else. :o

