Does Glucosamine/Chondroitin sulfate actually work?

It's not gonna do anything for the lumbar spine, anyway. Completely different problem.

Don't take it for backache. Take it for weightbearing contact joints. If you feel better and function better in 2 months, yay! If not, your diet is already adequate for your current bodily demands and don't waste your money.

Move it or lose it!

(got a backache? Do 10 yoga cobras. Feel better? Move better? Good. Do 10 of them, every two hours during the day and also when you feel pain, until you've had no pain for a full week. Don't feel better? Bummer. Go to a PT and say "I've got a lumbar derangement that doesn't respond to extension." That'll be $263, please.)

My totally unscientific study. I'm 45, almost 46 and getting a bit creaky, but insist on continuing my high impact activities, such as Zumba, running, Turbo Fire... Without it, I have annoying aches - not bad enough to be pain, but enough to keep some of my high impact from being attainable. I started taking it, just to see and 3 weeks later, my knees are more stable, my ankles don't bother me (I tend to suffer from Achilles tendon) and feet are happy. Seriously, I love the stuff. I feel like I lost 10 years off my age. So, to me it's worth it. But like every thing else Your Mileage May Vary.

My rhuematologist (regular M.D.) recommends Cosamin ASU joint health supplement. It has glucosamine & chondroitin but also an avocado/soybean additive. It has actually been shown to help arthritis.

I have arthritis all over my body and it does help me. Regular glucosamine/chondroitin/MSM does nothing. I also take meloxicam daily, which is a prescription anti-inflammatory (NSAID)

As far as aging knees & other high use joints - most people over 50 have all kinds of small tears & arthritic changes. It has been shown that many of those people don't have any symptoms at all. In fact, some of the worst x-rays of joints often don't correlate with any joint pain (or minimal).

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Originally Posted by Dogmama

My rhuematologist (regular M.D.) recommends Cosamin ASU joint health supplement. It has glucosamine & chondroitin but also an avocado/soybean additive. It has actually been shown to help arthritis.

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Where do you find this? My crunchy knees would like some relief please. :rolleyes:

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Originally Posted by bmccasland

Where do you find this? My crunchy knees would like some relief please. :rolleyes:

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+1 on that please!

I've had arthritis in my knees since mid-30s. I cycle to/from work 18 miles a day because cycling aggravates the pain far less than walking/standing/stairs (i.e. public transport) does. I still have to ice my knees morning and night or risk swelling.

I've tried glucosamine/chondroitin but it made me nauseous so I quit. Don't know if it would have actually helped or not if I'd carried on taking it.

My mom seems to think glucosamine/chondroitin does help her. (She's 75 years old, has had arthritis in her knees since her mid-30s like me. She had a knee replacement a few years ago, then was all set to have the second one done last year but torn rotator cuff took priority.)

As for me, I've been spending my summer thinking very seriously about proceeding this winter with an orthroscopic procedure that's been recommended by two different orthopaedic surgeons. But in the meantime, I'll have a hunt to find out if Cosamin ASU joint health supplement (or equivalent) is available in the UK. If it helps, it may only delay the inevitable, though, whereas I understand a successful keyhole procedure would turn back the clock on the pain by a few years. I'd be so happy to go back to just the clicking and grinding I had 5-6 years ago - if it meant I could walk the quarter mile to the end of the road without pain!

Are dietary sources mostly a matter of getting it directly from other critters' cartilage? Canned fish with bones, meat soups, that sort of thing?

Like Knot says...Move it or Lose it.
Every time i cut back on my fitness walks etc....within a month I get noticeably more stiff and achey- my hip joints, knees, etc. I beef up the walking and voila, no more problem.

i do take Glu/chond, and I feel it helps me. I can't tell you whether that's placebo effect or not.

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Originally Posted by beccaB

I have been taking a Glucosamine/chondroitin sulfate msm supplement for years. I though I would wean myself off it, but I am having pain again. The doctors are skeptical about it actually working, what do y'all think?

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Every answer you get here is anecdotal. Do a search of reputable (ie, not studies done by drug companies) studies for information.

In my own personal trial, Hyluronic Acid was more effective than Glucosamine or MSM (Chondroitin comes from animal sources so no go for me) when I had knee problems but to be honest now that I am riding like crazy, I sometimes forget to take it and have not had the pain return.

And, although I was told I had a great deal of arthritis due to injury and surgeries, my acupuncture/massage guy was able to work on my quads and relieve "knee" pain. If your quads lock up it pulls on the knee, that is where you feel it. Something to think about too.

Right now I do my own massage by rolling on a hard foam roller to try and keep my quads loose and prevent knee pain.

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Originally Posted by arielmoon

And, although I was told I had a great deal of arthritis due to injury and surgeries, my acupuncture/massage guy was able to work on my quads and relieve "knee" pain. If your quads lock up it pulls on the knee, that is where you feel it. Something to think about too.

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Yup, been that route.

My arthritis is due to mal-formation of the joint in several separate ways. This was diagnosed by x-ray and MRI when I was 11 - but the orthopaedist (in the USA) 'neglected' to mention to my parents 'oh and guess what, she'll get arthritis at a ridiculously young age because of this'. Xrays and MRI here in England last year showed exactly the same mal-formations... plus degenerative arthritis. :(

PT and stretching regime helped somewhat when I first began cycling a year ago. I was told it was especially important to stretch hamstrings & quads and the PT did a few other things each week to relieve pressure in the joint / on the back of the patella. However, the PT and the surgeon said cycling was the very best thing I could be doing and felt that, if I kept it up (which I have), cycling would accomplish far more in strengthening and supporting the entire knee joint than PT and/or acupuncture ever could.

But the improvement and relief I got from cycling (which was both marked and revelatory) peaked this spring and then declined. It's as if I passed through that stage of "getting stronger = less pain" and now I've arrived at "knee pain now preventing me from getting any stronger than this". :(

My mileage continues to go up each week... and I am wayyyyy fitter and stronger and smarter with gears/hills/etc.... which only tantalizes me with the dream of how much MORE cycling I could be doing... how much faster and stronger I could be... if not for the bl**dy knees.

Hence the surgical option coming back onto my radar.

From what I remember from the little research I've done, it seems to help moving joints that already have arthritic tendencies. So, it helps me. I doubt it would help for just general creaky-ness.

And so what if it is a placebo effect? If believing it helps gets you up and moving, then it really is helping. Moving has been shown to keep joints, well, moving.

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Originally Posted by bmccasland

Where do you find this? My crunchy knees would like some relief please. :rolleyes:

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The cheapest place I found it was on Amazon.

http://www.amazon.com/gp/product/B000WJLZ0I/

Note that it is Cosamin ASU, not Cosamin DS.

I think like so many of you have said, it varies with the individual and the joint affected. I too, have had several dogs that it has definitely helped!

AS for me, Knot I'm one of those bone on bone knee kind of girls... have been since I was 21.(I'm 52 now) All of my surgeons have told me that it wouldn't help, that I simply had too much damage. The surgeons also mentioned that as a 21 year old student athlete, that I was definitely a candidate for a knee replacement... On a whim, I thought that I would try it a few years ago, I figured if it didn't help after a couple of months then I could stop. Well, the reality is that it DOES help me, and if I get busy and forget to take it for several days, then it reminds me. I'm one of those people that while going downstairs, everyone can hear me... and it's a standing joke that I definitely can't sneak up on anyone. I live in a 3 story house, so I'm up and down stairs all the time.. so I'm thankful for it. Does it make me have knees like I did before alll the surgeries? NO, but it does make life more tolerable for me.:cool:

Another anecdote. Gluc/Chon has helped my knee pain. That as well as all of my running/cycling/CrossFit - combination therapy.:D Like you Ridebikeme, if I forget the supplement for a couple of days, the knees complain. It does absolutely nothing for my back pain (which is prloapsed disc every now and then) and nothing for supraspinatous (currently driving me nuts). But my knees are telling me they are very happy. Like Knot says- if it works, it works.